Vilon — Research, Dosing & Price Guide

Vilon (Lys-Glu) is the shortest bioregulator peptide in the Khavinson family — a dipeptide designed to support immune function and thymic activity. Despite its minimal size (just two amino acids), research suggests it can modulate gene expression in immune cells. It is used as a thymic bioregulator in Russian anti-aging and immunological protocols.

Vilon's dipeptide sequence (lysine-glutamic acid) is proposed to interact with DNA in the promoter regions of genes involved in T-cell development and immune regulation. Research by Khavinson's group suggests that even dipeptides can serve as epigenetic modulators, interacting with histone proteins and DNA to influence chromatin accessibility and gene transcription. Vilon specifically targets genes involved in thymic epithelial cell function and T-lymphocyte maturation. It may support the expression of cytokines (IL-2, IL-7) necessary for T-cell proliferation and differentiation. The extremely small size allows for oral bioavailability and potential blood-brain barrier penetration.

• Khavinson et al. showed that the Lys-Glu dipeptide can interact with DNA and modulate gene expression in lymphoid tissue in cell culture studies
• Russian clinical studies report improved immune parameters (T-cell counts, CD4/CD8 ratios) in elderly patients after vilon courses
• Research on dipeptide bioregulators shows they can cross cell membranes and enter the nucleus to interact with chromatin
• Studies in immunocompromised animal models showed vilon partially restored thymic function and T-cell output
• The concept of ultra-short peptide bioregulation has been published in over 100 papers from the St. Petersburg institute

• Oral: 1–2 capsules (10–20 mg) daily for 10–30 days
• Injectable: 10 mcg subcutaneously every other day for 10–20 days
• Repeat courses every 3–6 months
• Take on an empty stomach
• Often combined with thymogen and thymosin alpha-1 for comprehensive immune bioregulation
• Can be used as part of a seasonal immune support program

Known Side Effects

• No significant side effects reported in available literature
• Dipeptide structure ensures minimal immunogenicity
• No adverse immune reactions documented
• Extremely well tolerated across all age groups in Russian clinical experience

Safety Profile

Vilon is one of the simplest and safest bioregulator peptides, consisting of just two naturally occurring amino acids. Its safety profile is excellent based on decades of Russian clinical use. No significant adverse events have been reported. The dipeptide is rapidly metabolized and has no accumulation risk. Western validation data is limited. No contraindications are established, though caution is advised in autoimmune conditions as with all immunomodulatory agents.

Bioregulator effects are gradual and subtle. No dramatic acute effects expected. Over 10–30 day courses, immune function may gradually normalize at the cellular level. Benefits are most apparent in elderly or immunocompromised individuals. Repeat courses over months to years may produce cumulative improvements in immune resilience. Some users report fewer infections and improved general vitality after multiple courses.

Prices sourced from peptides.gg marketplace. Prices may vary.